Symbol Name ID

Prnp prion protein MGI:97769

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28 matching Alleles (1 Gene/Marker represented)

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                                   Allele Symbol
Name                                      Chr                                                                           Synonyms                                                                                     Category                           Phenotypic Classes                           Human Diseases           

Prnpa
prion protein; a                                                                     2                                                                                                                                                               Spontaneous                     immune                                                                              

Prnpb
prion protein; b                                                                     2                                                                                                                                                               Spontaneous                     immune                                                                              

Prnpc
prion protein; c                                                                     2                                                                                                                                                               Spontaneous                     immune                                                                              

Prnp/Prndtm1Aag
prion protein; targeted mutation 1, Adriano Aguzzi                         2    Prno                                                                                                                                                       Targeted (knock-out)            reproductive                                                                        

Prnptm1Aag
prion protein; targeted mutation 1, Adriano Aguzzi                              2    PrnpGFP                                                                                                                                                    Targeted (Reporter)                                                                                                 

Prnptm1Canc
prion protein; targeted mutation 1, Enrico Cancellotti                         2    G1                                                                                                                                                         Targeted (knock-in)             no abnormal phenotype observed                                                      

Prnptm1Cwe
prion protein; targeted mutation 1, Charles Weissmann                           2    Prnp-, Prn-p0, Prnp0, Prnp0 Zurich I, Prnptm1Zrch, Prnp trn1Zrch, PrnpZH1, PrP0, PrPC-KO, PrPC Zrch-1, Zrch 1 Prnp0, ZrchI Prnp-, Zrch Prnp0, Zurich line  Targeted (knock-out)            behavior, homeostasis, immune, nervous system                                       

Prnp/Prndtm1Dwm
prion protein; targeted mutation 1, David W Melton                         2    Prnp-/Prnd-                                                                                                                                                Targeted (knock-out)            reproductive                                                                        

Prnptm1Edin
prion protein; targeted mutation 1, Edinburgh University                       2    101LL, Prnpa101L, Rcm0                                                                                                                                     Targeted (knock-in)             immune                                                                              

Prnptm1Ito
prion protein; targeted mutation 1, Shigeyoshi Itohara                          2    Prnp-, Prnp0, Rikn Prnp-                                                                                                                                   Targeted (knock-out)            behavior                                                                            

Prnptm1Lnq
prion protein; targeted mutation 1, Susan Lindquist                             2    PrP3F4WT                                                                                                                                                   Targeted (knock-in)             immune                                                                              

Prnptm1Miy
prion protein; targeted mutation 1, Tsutomu Miyamoto                            2    Nagasaki, Ngsk Prnp0, Prnp-, PrP                                                                                                                           Targeted (knock-out)            behavior, immune, nervous system                                                    

Prnptm1(PRNP)Tkit
prion protein; targeted mutation 1, Tetsuyuki Kitamoto                   2    Hu-Ki, Ki-ChM                                                                                                                                              Targeted (knock-in)             immune                                         Creutzfeldt-Jakob Disease; CJD 123400

Prnptm1Rcm
prion protein; targeted mutation 1, Richard C Moore                             2    Prnpa[108F189V], PrP gtB                                                                                                                                   Targeted (knock-in)             immune                                                                              

Prnptm1Tuzi
prion protein; targeted mutation 1, Nadia L Tuzi                               2    Prpstop                                                                                                                                                    Targeted (knock-out)            immune                                                                              

Prnptm2.1Cwe
prion protein; targeted mutation 2.1, Charles Weissmann                       2    Prnp lox1 (ZH II), Prnp- Zurich II                                                                                                                         Targeted (knock-out)            behavior, muscle, nervous system                                                    

Prnptm2Canc
prion protein; targeted mutation 2, Enrico Cancellotti                         2    G2                                                                                                                                                         Targeted (knock-in)             no abnormal phenotype observed                                                      

Prnptm2Cwe
prion protein; targeted mutation 2, Charles Weissmann                           2    Prnp lox2                                                                                                                                                  Targeted (Floxed/Frt)           no abnormal phenotype observed                                                      

Prnptm2Edin
prion protein; targeted mutation 2, Edinburgh University                       2    mPrP0/0, NPU, PrnpEdbg, Prnp- Edinburgh, PrP-                                                                                                              Targeted (knock-out)            cellular, immune, nervous system                                                    

Prnptm2Lnq
prion protein; targeted mutation 2, Susan Lindquist                             2    PrP3F4FFI                                                                                                                                                  Targeted (knock-in)             behavior, homeostasis, nervous system          Fatal Familial Insomnia; FFI 600072  

Prnptm2(PRNP*129M)Tkit
prion protein; targeted mutation 2, Tetsuyuki Kitamoto              2    Ki-Hu129M                                                                                                                                                  Targeted (knock-in)             immune                                                                              

Prnptm2Rcm
prion protein; targeted mutation 2, Richard C Moore                             2    Rcm0                                                                                                                                                       Targeted (knock-out)            behavior                                                                            

Prnptm2Tuzi
prion protein; targeted mutation 2, Nadia L Tuzi                               2    Prpfl                                                                                                                                                      Targeted (knock-out)            immune                                                                              

Prnptm3Canc
prion protein; targeted mutation 3, Enrico Cancellotti                         2    G3                                                                                                                                                         Targeted (knock-in)             no abnormal phenotype observed                                                      

Prnptm3(PRNP*129V)Tkit
prion protein; targeted mutation 3, Tetsuyuki Kitamoto              2    Ki-Hu129V                                                                                                                                                  Targeted (knock-in)             hematopoietic, immune, nervous system                                               

Prnptm4(PRNP)Tkit
prion protein; targeted mutation 4, Tetsuyuki Kitamoto                   2    Ki-Bov                                                                                                                                                     Targeted (knock-in)             immune                                                                              

Prnptm5(PRNP*)TKit
prion protein; targeted mutation 5, Tetsuyuki Kitamoto                  2    Ki-Hu129M4R                                                                                                                                                Targeted (knock-in)             no abnormal phenotype observed                                                      

Prnptm1e(EUCOMM)Hmgu
prion protein; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH  2                                                                                                                                                               Targeted (Reporter)
(Cell Line)