Symbol Name ID

Smo smoothened homolog (Drosophila) MGI:108075

---

5 matching Alleles (1 Gene/Marker represented)

---

                                Allele Symbol
Name                                   Chr            Synonyms                   Category                                                                                                                                                                                                                                                                                  Phenotypic Classes                                                                                                                                                                                                                                                                                                 Human Diseases                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       Allelic Composition
(Genetic Background)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               

Smobnb
smoothened homolog (Drosophila); bent body                                    6    bnb                          Chemically induced (ENU)  ['embryogenesis, cardiovascular, growth/size, limbs/digits/tail, homeostasis', 'lethality/prenatal-perinatal, embryogenesis, nervous system', 'cardiovascular, lethality/prenatal-perinatal, nervous system, embryogenesis', 'lethality/prenatal-perinatal']                                                                                                                                                                                                                                                                                                        ['', '', '', '']                                              ['Smobnb/Smobnb


Allele Symbol
Gene; Allele Name
Chr
Synonyms
Category
Observed Phenotypes in Mouse
Allelic Composition
(Genetic Background)


Affected Anatomical Systems
Similar Human Diseases

', 'Smobnb/Smobnb
   
(involves: C3HeB/FeJ * C57BL/6J)
', 'Ift172wim/Ift172wim
Smobnb/Smobnb
   
(involves: C57BL/6J)
', 'Kif7maki/Kif7maki
Smobnb/Smobnb
Tg(Hlxb9-GFP)1Tmj/?
   
(involves: C57BL/6J * FVB/N)
']                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   

Smotm1.1Pab
smoothened homolog (Drosophila); targeted mutation 1.1, Philip A Beachy  6    Smo-                         Targeted (knock-out)      ['embryogenesis, nervous system, cardiovascular, craniofacial, growth/size, vision/eye']                                                                                                                                                                                                                                                                                                                                                                                                                                                                            ['']                                                          ['Smotm1.1Pab/Smotm1.1Pab
   
(Not Specified)
']                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        

Smotm1Amc
smoothened homolog (Drosophila); targeted mutation 1, Andrew P McMahon     6    Smo-, Smon, Smonull, Smorec  Targeted (knock-out)      ['embryogenesis', 'nervous system, embryogenesis, growth/size', 'nervous system', 'lethality/postnatal, nervous system', 'embryogenesis', 'nervous system, embryogenesis', 'lethality/postnatal, skeleton, limbs/digits/tail', 'skeleton, limbs/digits/tail', 'skeleton, limbs/digits/tail', 'cardiovascular, embryogenesis, craniofacial', 'nervous system, cardiovascular, homeostasis, embryogenesis', 'lethality/prenatal-perinatal, craniofacial, skeleton', 'none', '', 'craniofacial, hearing/vestibular/ear, digestive/alimentary, respiratory, skeleton']  ['', '', '', '', '', '', '', '', '', '', '', '', '', '', '']  ['Smotm1Amc/Smotm1Amc
   
(involves: 129X1/SvJ * C57BL/6)
', 'Smotm1Amc/Smotm1Amc
   
(involves: 129X1/SvJ * CD-1)
', 'Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg
Smotm1Amc/Smotm1Amc
   
(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
', 'Smotm1Amc/Smotm2Amc
Tg(Nes-cre)1Kln/0
   
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL * Swiss Webster)
conditionally targeted
', 'Bmp4tm2Blh/Bmp4+
Smotm1Amc/Smotm1Amc
   
(involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
', 'Kif7tm1.2Hui/Kif7tm1.2Hui
Smotm1Amc/Smotm1Amc
   
(involves: 129S6/SvEvTac * 129X1/SvJ * CD-1)
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)10Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)15Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)3Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Isl1tm1(cre)Sev/Isl1+
Smotm1Amc/Smotm2Amc
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm1Amc
Tulp3hhkr/Tulp3hhkr
   
(involves: 129X1/SvJ * C3H/HeH * C57BL/6)
', 'Smotm1Amc/Smotm2Amc
Tg(KRT14-cre)1Amc/0
   
(involves: 129X1/SvJ * C57BL/6 * CBA)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
   
(involves: 129X1/SvJ * CD-1)
conditionally targeted
', 'Smotm1Amc/Smotm1Amc
Tg(Ipf1-cre)1Tuv/0
   
(involves: 129X1/SvJ * FVB/N)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Wnt1-cre)11Rth/?
   
(involves: C57BL/6J * CBA/J)
conditionally targeted
']

Smotm1Pab
smoothened homolog (Drosophila); targeted mutation 1, Philip A Beachy      6                                 Targeted (Floxed/Frt)     ['']                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                ['']                                                          ['Smotm1Pab/Smo+
   
(Not Specified)
']                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 

Smotm2Amc
smoothened homolog (Drosophila); targeted mutation 2, Andrew P McMahon     6    Smoc, Smof, Smofl, Smoflox   Targeted (Floxed/Frt)     ['nervous system, embryogenesis', 'lethality/postnatal, nervous system', 'skeleton, craniofacial', 'lethality/postnatal, skeleton, limbs/digits/tail', 'skeleton, limbs/digits/tail', 'skeleton, limbs/digits/tail', 'none', 'cardiovascular, embryogenesis, craniofacial', 'lethality/prenatal-perinatal, craniofacial, skeleton', 'nervous system', 'nervous system', 'none', 'craniofacial, hearing/vestibular/ear, digestive/alimentary, respiratory, skeleton']                                                                                                ['', '', '', '', '', '', '', '', '', '', '', '', '']          ['En1tm2(cre)Wrst/?
Gli3tm1Alj/Gli3tm1Alj
Smotm2Amc/Smotm2Amc
   
(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
', 'Smotm1Amc/Smotm2Amc
Tg(Nes-cre)1Kln/0
   
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL * Swiss Webster)
conditionally targeted
', 'Gt(ROSA)26Sortm6Dym/?
Smotm2Amc/Smotm2Amc
Sox9tm3(cre)Crm/Sox9+
   
(involves: 129S7/SvEvBrd * 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)10Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)15Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Col2a1-cre)3Amc/0
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm2Amc/Smotm2Amc
Tg(mI56i-cre,EGFP)1Kc/?
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Isl1tm1(cre)Sev/Isl1+
Smotm1Amc/Smotm2Amc
   
(involves: 129X1/SvJ)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(KRT14-cre)1Amc/0
   
(involves: 129X1/SvJ * C57BL/6 * CBA)
conditionally targeted
', 'Smotm2Amc/Smotm2Amc
Tg(Nes-cre)1Kln/0
   
(involves: 129X1/SvJ * C57BL/6 * SJL)
conditionally targeted
', 'Olig3tm1(cre)Ynka/Olig3+
Smotm2Amc/Smotm2Amc
   
(involves: 129X1/SvJ * C57BL/6J)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
   
(involves: 129X1/SvJ * CD-1)
conditionally targeted
', 'Smotm1Amc/Smotm2Amc
Tg(Wnt1-cre)11Rth/?
   
(involves: C57BL/6J * CBA/J)
conditionally targeted
']