Symbol
Name
ID
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Synonyms
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1500041B07Rik, D630021H01Rik, Mbd5, WBP10
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(38)
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Alleles
and
phenotypes
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All alleles(16) :
Targeted, knock-out(5)
Targeted, other(7)
Gene trapped(4)
| Female mice homozygous or male mice hemizygous for a null allele exhibit premature death, behavioral and neurological abnormalities, abnormal nervous system phenotypes, abnormal breathing, and abnormal hearing. Heterozygous mice exhibit similar behavioral and neurological abnormalities. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (6)
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Polymorphisms
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All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(93 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (17 records)
Data Summary:
Assays (32)
Results (448)
Tissues (207)
Images (18)
Theiler Stages: 8,9,13,15,17,18,20,22,24,28
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Assay Type |
Assays |
|
Results |
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RT-PCR |
28 |
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128 |
| |
RNA in situ |
3 |
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315 |
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Northern blot |
1 |
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5 |
cDNA source data(14)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(26)
Genomic(5)
cDNA(15)
Primer pair(6)
Microarray probesets(3)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001739 |
Methyl-CpG DNA binding |
| IPR017353 |
Methyl-CpG binding protein MeCP2 |
| IPR017956 |
AT hook, DNA-binding motif |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:10374
Klemsz MJ et al.,
"The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene [see comments]"
Cell 1990 Apr 6;61(1):113-24
(Latest)
J:153250
Taneja P et al.,
"Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome."
J Neurosci 2009 Sep 30;29(39):12187-95
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All references(119)
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Other
accession IDs
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MGD-MRK-16719, MGI:2148036, MGI:2442482, MGI:2442970
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