Symbol
Name
ID
|
|
|
Synonyms
|
ABC1
|
|
Genetic Map
|
|
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Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(35)
|
Alleles
and
phenotypes
|
All alleles(8) :
Targeted, knock-out(5)
Targeted, other(1)
Gene trapped(1)
Chemically induced(1)
| Many homozygous null mutants die perinatally with placental defects. Survivors show altered steroidogenesis, defective lipid export in Golgi, low serum cholesterol, lipid accumulation in macrophages and lung, reduced fertility and kidney and heart defects. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (6)
Phenotype Images (1)
|
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Polymorphisms
|
RFLP(1)
SNPs within 2kb(1004 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (5 records)
Data Summary:
Assays (1)
Results (2)
Tissues (1)
Images (2)
Theiler Stages: 21
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
2 |
cDNA source data(100)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(101)
cDNA(100)
Other(1)
Microarray probesets(4)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:24443
Higgins CF,
"ABC transporters: from microorganisms to man."
Annu Rev Cell Biol 1992;8():67-113
(Latest)
J:153479
Samyn H et al.,
"Reduction of HDL levels lowers plasma PLTP and affects its distribution among lipoproteins in mice."
Biochim Biophys Acta 2009 Aug;1791(8):790-6
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All references(102)
|
Other
accession IDs
|
MGD-MRK-16392
|
