Symbol
Name
ID
|
|
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Synonyms
|
Wnt-7b
|
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Genetic Map
|
|
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Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(27)
|
Alleles
and
phenotypes
|
All alleles(8) :
Targeted, knock-out(2)
Targeted, other(5)
Gene trapped(1)
| Homozygous null embryos die at midgestational stages due to placental abnormalities involving the fusion of the chorion and allantois. Mice homozygous for a truncated allele display neonatal lethality, respiratory failure, and lung hemorrhage. |
|
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Polymorphisms
|
All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(176 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (97 records)
Data Summary:
Assays (24)
Results (288)
Tissues (161)
Images (60)
Theiler Stages: 1,2,3,4,5,8,9,11,13,15,16,17,19,20,21,22,23,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
1 |
| |
RT-PCR |
7 |
|
32 |
| |
RNA in situ |
14 |
|
248 |
| |
Immunohistochemistry |
1 |
|
5 |
| |
RNase protection |
1 |
|
2 |
cDNA source data(54)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(71)
cDNA(58)
Primer pair(9)
Other(4)
Antibodies(1)
Microarray probesets(3)
|
Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:10971
Gavin BJ et al.,
"Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development."
Genes Dev 1990 Dec;4(12B):2319-32
(Latest)
J:153098
Goss AM et al.,
"Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut."
Dev Cell 2009 Aug;17(2):290-8
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All references(120)
|
Other
accession IDs
|
MGD-MRK-15447, MGD-MRK-15457
|
