Symbol
Name
ID
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Synonyms
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Wnt-7b
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(27)
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Alleles and phenotypes
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All alleles(8) :
Targeted, knock-out(2)
Targeted, other(5)
Gene trapped(1)
| Homozygous null embryos die at midgestational stages due to placental abnormalities involving the fusion of the chorion and allantois. Mice homozygous for a truncated allele display neonatal lethality, respiratory failure, and lung hemorrhage. |
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Polymorphisms
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All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(176 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (102 records)
Data Summary:
Assays (26)
Results (307)
Tissues (173)
Images (76)
Theiler Stages: 1,2,3,4,5,8,9,11,13,15,16,17,19,20,21,22,23,24,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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1 |
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RT-PCR |
7 |
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32 |
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RNA in situ |
16 |
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267 |
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Immunohistochemistry |
1 |
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5 |
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RNase protection |
1 |
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2 |
cDNA source data(55)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular reagents
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All nucleic(74)
cDNA(59)
Primer pair(10)
Other(5)
Antibodies(1)
Microarray probesets(3)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:10971
Gavin BJ et al.,
"Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development."
Genes Dev 1990 Dec;4(12B):2319-32
(Latest)
J:155332
Fotaki V et al.,
"Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon."
Dev Dyn 2010 Jan;239(1):284-96
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All references(126)
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Other accession IDs
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MGD-MRK-15447, MGD-MRK-15457
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