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Wnt6 Gene Detail
 Symbol
Name
ID
Wnt6
wingless-related MMTV integration site 6
MGI:98960


Nomenclature History
Synonyms Wnt-6
Genetic Map
Chromosome 1
Syntenic
 
Mapping data( 1)
Sequence Map
Chr1:74818466-74831893 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: int-1 transforming protein
TreeFam: TF105310
Sequences
Representative Sequences Length Strain/Species Flank
genomic 22420 NCBI Gene Model | MGI Sequence Detail 13428 C57BL/6J ± Kb
transcript NM_009526 RefSeq | MGI Sequence Detail 2068 C57BL/6
polypeptide P22727 UniProt | EBI | MGI Sequence Detail 364 Not Applicable
For the selected sequences
All sequences(17)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Homozygous null mutants have no obvious pituitary phenotype.
Polymorphisms SNPs within 2kb(10 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell-cell signaling, multicellular organismal development...
Component extracellular region, proteinaceous extracellular matrix...
Function protein binding, receptor binding...
External Resources: FuncBase
Expression Literature Summary: (53 records)
Data Summary: Assays (19)    Results (186)    Tissues (138)    Images (49)
Theiler Stages: 1,2,3,4,5,6,8,9,11,13,15,17,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 9   33
      RNA in situ 9   151
      RNase protection 1   2
cDNA source data(21)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(32) cDNA(22) Primer pair(7) Other(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000033227
DoTS DT.487555, DT.50314912
Consensus CDS Project CCDS15056.1
UniGene 268282
DFCI TC1588960, TC1660613
NIA Mouse Gene Index U042178
Entrez Gene 22420
International Mouse Knockout Project Status Wnt6
Protein
domains
InterPro ID Description
IPR005816 Secreted growth factor Wnt protein
IPR005817 Wnt superfamily
IPR009143 Wnt-6 protein
IPR018161 Secreted growth factor Wnt protein, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:10971 Gavin BJ et al., "Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development." Genes Dev 1990 Dec;4(12B):2319-32
(Latest) J:155223 Suomalainen M et al., "Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells." Dev Dyn 2009 Oct 5;239(1):364-372
All references(64)
Other
accession IDs
MGD-MRK-15445, MGD-MRK-15455, MGI:2138090

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory