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Wnt5b Gene Detail
 Symbol
Name
ID
Wnt5b
wingless-related MMTV integration site 5B
MGI:98959

Nomenclature History
Synonyms Wnt-5b
Genetic Map
Chromosome 6
56.2 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr6:119382549-119494336 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Wnt5b ± 2 cM)
Protein SuperFamily: int-1 transforming protein
TreeFam: TF105310
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000027047 VEGA Gene Model | MGI Sequence Detail 111788 C57BL/6J ± Kb
transcript NM_009525 RefSeq | MGI Sequence Detail 2384 C57BL/6
polypeptide P22726 UniProt | EBI | MGI Sequence Detail 359 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Mice homozygous for a knock-out allele exhibit normal numbers of thoracic motor neurons and proportions of motor columnar subtypes.
Polymorphisms SNPs within 2kb(504 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell-cell signaling, multicellular organismal development...
Component extracellular region, proteinaceous extracellular matrix...
Function protein binding, receptor binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (42 records)
Data Summary: Assays (14)    Results (255)    Tissues (213)    Images (39)
Theiler Stages: 1,2,3,4,5,8,9,11,13,15,17,19,20,21,22,23,24,26,28
  Assay Type Assays   Results
      RT-PCR 6   75
      RNA in situ 7   178
      RNase protection 1   2
cDNA source data(46)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(60) cDNA(49) Primer pair(9) Other(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030170
DoTS DT.101367707, DT.91592823, DT.94161050
Consensus CDS Project CCDS20474.1
UniGene 321818
DFCI TC1581436
NIA Mouse Gene Index U027798
Entrez Gene 22419
VEGA Gene Model OTTMUSG00000027047
International Mouse Knockout Project Status Wnt5b
Protein
domains
InterPro ID Description
IPR005816 Secreted growth factor Wnt protein
IPR005817 Wnt superfamily
IPR018161 Secreted growth factor Wnt protein, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:10971 Gavin BJ et al., "Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development." Genes Dev 1990 Dec;4(12B):2319-32
(Latest) J:155223 Suomalainen M et al., "Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells." Dev Dyn 2009 Oct 5;239(1):364-372
All references(53)
Other
accession IDs 		MGD-MRK-15444, MGD-MRK-15454, MGI:2141692
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory