Symbol
Name
ID
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Synonyms
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8030457G12Rik, Wnt-5a
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(22)
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Alleles
and
phenotypes
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All alleles(1) :
Targeted, knock-out(1)
| Homozygous mutants exhibit caudal truncation with shortened anterior-posterior axis, truncation of the snout, tongue and mandible, short fore- and hindlimbs, which lack digits, absent genital tubercle and lung abnormalities. Mutants die perinatally. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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RFLP(4)
SNPs within 2kb(109 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (132 records)
Data Summary:
Assays (38)
Results (500)
Tissues (295)
Images (76)
Theiler Stages: 1,2,3,4,5,8,9,11,13,14,15,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
18 |
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249 |
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RNA in situ |
19 |
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245 |
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Immunohistochemistry |
1 |
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6 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(48)
Genomic(1)
cDNA(21)
Primer pair(19)
Other(7)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR005816 |
Secreted growth factor Wnt protein |
| IPR018161 |
Secreted growth factor Wnt protein, conserved site |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:10971
Gavin BJ et al.,
"Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development."
Genes Dev 1990 Dec;4(12B):2319-32
(Latest)
J:153152
Tai CC et al.,
"Wnt5a knock-out mouse as a new model of anorectal malformation."
J Surg Res 2009 Oct;156(2):278-82
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All references(168)
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Other
accession IDs
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MGD-MRK-15443, MGD-MRK-15453, MGI:1924815
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