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Thy1 Gene Detail
 Symbol
Name
ID
Thy1
thymus cell antigen 1, theta
MGI:98747


Nomenclature History
STS D9Nds3
Synonyms CD90, T25, theta, Thy 1.2, Thy-1, Thy-1.2, Thy1.1, Thy1.2
Genetic Map
Chromosome 9
26.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 54)

Sequence Map
Chr9:43851467-43856662 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Thy1 ± 2 cM)
Protein SuperFamily: Thy-1 membrane glycoprotein
TreeFam: TF336059
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000016734 VEGA Gene Model | MGI Sequence Detail 5196 C57BL/6J ± Kb
transcript NM_009382 RefSeq | MGI Sequence Detail 1753 C57BL/6
polypeptide P01831 UniProt | EBI | MGI Sequence Detail 162 Not Applicable
For the selected sequences
All sequences(30)
Alleles
and
phenotypes
All alleles(4) : Targeted, knock-out(2) Gene trapped(1) Other(1)
Homozygous null mice are viable, fertile, and display no abnormalities in the brain and spinal cord, have normal axonal development and regeneration and no behavioral abnormalities. Long term potentiation is inhibited in the dentate gyrus.
Polymorphisms All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(83 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(10)
Process angiogenesis, negative regulation of T cell receptor signaling pathway...
Component anchored to external side of plasma membrane, anchored to membrane...
External Resources: MouseFunc
Expression Literature Summary: (19 records)
Data Summary: Assays (6)    Results (37)    Tissues (17)    Images (14)
Theiler Stages: 20,22,23,24,26,28
  Assay Type Assays   Results
      RT-PCR 3   14
      RNA in situ 2   15
      Immunohistochemistry 1   8
cDNA source data(52)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(78) Genomic(18) cDNA(55) Primer pair(4) Other(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000032011
DoTS DT.101337538, DT.533681, DT.94314670
UniGene 3951
DFCI TC1577066, TC1628688, TC1715283
Entrez Gene 21838
VEGA Gene Model OTTMUSG00000016734
International Mouse Knockout Project Status Thy1
Protein
domains
InterPro ID Description
IPR003596 Immunoglobulin V-set, subgroup
IPR007110 Immunoglobulin-like
IPR013151 Immunoglobulin
Graphical View of Protein Domain Structure
References
(Earliest) J:24839 REIF AE et al., "THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES." J Exp Med 1964 Sep 1;120():413-33
(Latest) J:152162 Geller SF et al., "CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development." PLoS Genet 2009 Aug;5(8):e1000607
All references(131)
Other
accession IDs
MGD-MRK-15100, MGD-MRK-15102

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory