Symbol
Name
ID
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Synonyms
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pp60c-src
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(40)
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Alleles and phenotypes
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All alleles(67) :
Targeted, knock-out(1)
Gene trapped(66)
| Homozygotes for a targeted null mutation exhibit growth retardation, failure of tooth eruption, osteopetrosis with lack of secondary bone resorption, and lethality at 3-4 weeks. |
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Polymorphisms
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RFLP(12)
SNPs within 2kb(246 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (18 records)
Data Summary:
Assays (3)
Results (105)
Tissues (52)
Images (15)
Theiler Stages: 22,23,24,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
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92 |
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RNA in situ |
1 |
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13 |
cDNA source data(90)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular reagents
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All nucleic(104)
Genomic(7)
cDNA(93)
Primer pair(1)
Other(3)
Microarray probesets(3)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:5972
Collett MS et al.,
"Protein kinase activity associated with the avian sarcoma virus src gene product."
Proc Natl Acad Sci U S A 1978 Apr;75(4):2021-4
(Latest)
J:153843
Yi Z et al.,
"A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells."
Blood 2009 Oct 8;114(15):3191-8
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All references(159)
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Other accession IDs
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MGD-MRK-14556, MGI:2139334
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