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Sox5 Gene Detail
 Symbol
Name
ID
Sox5
SRY-box containing gene 5
MGI:98367

Nomenclature History
Synonyms A730017D01Rik
Genetic Map
Chromosome 6
69.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr6:143776945-144730497 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Sox5 ± 2 cM)
Protein SuperFamily: transcription factor Sox5/Sox6/Sox13
TreeFam: TF320471
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000025246 VEGA Gene Model | MGI Sequence Detail 953553 C57BL/6J ± Kb
transcript NM_011444 RefSeq | MGI Sequence Detail 2917 C57BL/6
polypeptide P35710 UniProt | EBI | MGI Sequence Detail 763 Not Applicable
For the selected sequences
All sequences(46)
Alleles
and
phenotypes 		All alleles(6) : Targeted, knock-out(1) Targeted, other(2) Gene trapped(3)
Polymorphisms SNPs within 2kb(5453 from dbSNP Build 128)   SNPs within 2kb including multiple locations(5463)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cartilage development, cell fate commitment...
Component nucleus
Function DNA binding, promoter binding...
External Resources: FuncBase
Expression Literature Summary: (36 records)
Data Summary: Assays (17)    Results (217)    Tissues (187)    Images (24)
Theiler Stages: 2,3,4,5,13,17,18,20,21,22,23,26,28
  Assay Type Assays   Results
      RT-PCR 9   75
      In situ reporter (knock in) 1   6
      RNA in situ 5   130
      Northern blot 2   6
cDNA source data(40)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(52) cDNA(41) Primer pair(10) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000041540
DoTS DT.110498636, DT.40167928, DT.87056835, DT.87058469, DT.87068737, DT.91338328, DT.91387566, DT.91573194, DT.94140408, DT.94238186, DT.97388485
Consensus CDS Project CCDS39702.1
UniGene 1752
PDB 1I11
DFCI TC1584353, TC1591084, TC1595061, TC1598155, TC1611481, TC1618788, TC1663286
Entrez Gene 20678
VEGA Gene Model OTTMUSG00000025246
International Mouse Knockout Project Status Sox5
Protein
domains
InterPro ID Description
IPR000910 High mobility group, HMG1/HMG2
IPR009071 High mobility group, superfamily
Graphical View of Protein Domain Structure
References
(Earliest) J:1195 Denny P et al., "A conserved family of genes related to the testis determining gene, SRY." Nucleic Acids Res 1992 Jun 11;20(11):2887
(Latest) J:154601 Seuntjens E et al., "Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors." Nat Neurosci 2009 Nov;12(11):1373-80
All references(56)
Other
accession IDs 		MGD-MRK-14506, MGI:2141442, MGI:2442476
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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