Symbol
Name
ID
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Genetic Map
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Chromosome 15
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Syntenic
|
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Mapping data(
3)
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(23)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(1)
Gene trapped(2)
| Homozygotes for a targeted null mutation exhibit peripheral blood lymphocytosis, reductions in peritoneal B-1a lymphocytes, marginal zone lymphocytes, and IgM-secreting plasma cells, decreased levels of serum IgM and IgA, and abnormal T cell migration. |
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Polymorphisms
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SNPs within 2kb(95 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (4 records)
cDNA source data(75)
External Resources:
GEO
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Molecular
reagents
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All nucleic(76)
cDNA(76)
Microarray probesets(2)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:10526
Shirsat NV et al.,
"A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells."
Oncogene 1990 May;5(5):769-72
(Latest)
J:148437
Dumont C et al.,
"Rac GTPases play critical roles in early T-cell development."
Blood 2009 Apr 23;113(17):3990-8
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All references(61)
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Other
accession IDs
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MGD-MRK-13749, MGI:2145980, MGI:2146018
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