Symbol
Name
ID
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Synonyms
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D5Ertd559e
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(38)
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Alleles
and
phenotypes
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All alleles(40) :
Targeted, knock-out(3)
Targeted, other(4)
Gene trapped(33)
| Homozygotes for targeted null mutations exhibit embryonic lethality prior to embryonic day 9.5 with defects in gastrulation. Neutrophil specific knockout mice show defects in inflammatory recruitment and chemotactic responses. |
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Polymorphisms
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SNPs within 2kb(136 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (25 records)
Data Summary:
Assays (7)
Results (34)
Tissues (26)
Images (14)
Theiler Stages: 2,3,4,5,15,18,19,20,21,28
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Assay Type |
Assays |
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Results |
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Western blot |
4 |
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7 |
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RT-PCR |
1 |
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12 |
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RNA in situ |
1 |
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6 |
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Immunohistochemistry |
1 |
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9 |
cDNA source data(21)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(24)
Genomic(1)
cDNA(21)
Primer pair(2)
Antibodies(3)
Microarray probesets(3)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:724
Moll J et al.,
"The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments."
Oncogene 1991 May;6(5):863-6
(Latest)
J:154975
D'Amico G et al.,
"Regulation of lymphatic-blood vessel separation by endothelial Rac1."
Development 2009 Dec;136(23):4043-53
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All references(128)
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Other
accession IDs
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MGD-MRK-13748, MGI:1261850, MGI:2141016
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Analysis Tools
MGI BioMart
