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Pdha2 Gene Detail
 Symbol
Name
ID
Pdha2
pyruvate dehydrogenase E1 alpha 2
MGI:97533

Nomenclature History
Synonyms Pdhal
Genetic Map
Chromosome 3
cytoband B
 
Mapping data( 5)
Sequence Map
Chr3:140873534-140874709 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat; sheep    (Mammalian Orthology)
Protein SuperFamily: pyruvate dehydrogenase (lipoamide) alpha chain
TreeFam: TF300742
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000047674 Ensembl Gene Model | MGI Sequence Detail 1176 C57BL/6J ± Kb
transcript NM_008811 RefSeq | MGI Sequence Detail 2352 -
polypeptide P35487 UniProt | EBI | MGI Sequence Detail 391 Not Applicable
For the selected sequences
All sequences(14)
Polymorphisms SNPs within 2kb(37 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(11)
Process glycolysis, metabolic process...
Component intracellular membrane-bounded organelle, mitochondrion...
Function oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
cDNA source data(13)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(17) Genomic(2) cDNA(15)
Microarray probesets(2)
Pathways
acetyl-CoA biosynthesis (from pyruvate)
Other database
links
EC 1.2.4.1
Ensembl Gene Model ENSMUSG00000047674
DoTS DT.40158073
UniGene 4223
DFCI TC1584182
NIA Mouse Gene Index U024709
Entrez Gene 18598
International Mouse Knockout Project Status Pdha2
Protein
domains
InterPro ID Description
IPR001017 Dehydrogenase, E1 component
IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
Graphical View of Protein Domain Structure
References
(Earliest) J:10821 Brown RM et al., "Pyruvate dehydrogenase E1 alpha subunit genes in the mouse: mapping and comparison with human homologs." Somat Cell Mol Genet 1990 Sep;16(5):487-92
(Latest) J:151002 Pagliarini DJ et al., "A mitochondrial protein compendium elucidates complex I disease biology." Cell 2008 Jul 11;134(1):112-23
All references(9)
Other
accession IDs 		MGD-MRK-13220
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory