Symbol
Name
ID
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Synonyms
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1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Pax-6
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(50)
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Alleles
and
phenotypes
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All alleles(39) :
Targeted, knock-out(3)
Targeted, other(3)
Gene trapped(4)
Spontaneous(2)
Chemically induced(25)
Radiation induced(4)
| Null and hypomorphic mutants show a range of phenotypes from viable with small eyes and lens/cornea fusion to microphthalmia and cataract to embryonic or perinatal lethality with anophthalmia and severe craniofacial and forebrain defects. |
Associated Human Diseases (7)
Alleles Annotated to Human Diseases (13)
Phenotype Images (8)
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Polymorphisms
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All PCR and RFLP(2) :
PCR(1)
RFLP(1)
SNPs within 2kb(62 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (569 records)
Data Summary:
Assays (107)
Results (999)
Tissues (437)
Images (367)
Theiler Stages: 2,3,4,5,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
2 |
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5 |
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RT-PCR |
10 |
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62 |
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RNA in situ |
66 |
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764 |
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Immunohistochemistry |
23 |
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102 |
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Northern blot |
4 |
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35 |
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RNase protection |
2 |
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31 |
cDNA source data(36)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(92)
Genomic(11)
cDNA(45)
Primer pair(14)
Other(22)
Antibodies(10)
Microarray probesets(7)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:12101
Roberts RC,
"Small-eyes, a new dominant mutant in the mouse."
Genet Res 1967;9():121-122
(Latest)
J:153566
Fujimura N et al.,
"Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium."
Dev Biol 2009 Oct 1;334(1):31-45
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All references(755)
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Other
accession IDs
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MGD-MRK-13149, MGD-MRK-13158, MGD-MRK-14366, MGD-MRK-8831, MGI:2442292, MGI:3529952
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