Symbol
Name
ID
|
|
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Synonyms
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Pax-3
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(32)
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Alleles
and
phenotypes
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All alleles(26) :
Targeted, knock-out(1)
Targeted, other(13)
Spontaneous(5)
Chemically induced(2)
Radiation induced(6)
| Effects on homzygotes for mutations in this gene vary in severity and include embryonic to perinatal death, malformations of neural tube, spinal ganglia, heart, vertebral column, hindbrain and limb musculature. Heterozygotes have white belly spots and variable spotting on the back and extremeties. |
Associated Human Diseases (3)
Alleles Annotated to Human Diseases (5)
Phenotype Images (1)
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Polymorphisms
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All PCR and RFLP(7) :
PCR(1)
RFLP(6)
SNPs within 2kb(370 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
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Literature Summary: (251 records)
Data Summary:
Assays (71)
Results (490)
Tissues (182)
Images (186)
Theiler Stages: 11,13,14,15,16,17,18,19,20,21,22,23,25,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
11 |
|
47 |
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RNA in situ |
53 |
|
412 |
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Immunohistochemistry |
3 |
|
15 |
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Northern blot |
3 |
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12 |
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RNase protection |
1 |
|
4 |
cDNA source data(26)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(60)
Genomic(2)
cDNA(37)
Primer pair(10)
Other(11)
Antibodies(3)
Microarray probesets(3)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:12957
Russell WL,
"Splotch, a new mutation in the house mouse, Mus musculus."
Genetics 1947;32():102
(Latest)
J:154124
Abou-Khalil R et al.,
"Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal."
Cell Stem Cell 2009 Sep 4;5(3):298-309
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All references(432)
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Other
accession IDs
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MGD-MRK-13146, MGD-MRK-13155, MGD-MRK-14511
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