Symbol
Name
ID
|
|
|
STS
|
D10Mit112
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|
Synonyms
|
Tg.413d
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(16)
|
Alleles
and
phenotypes
|
All alleles(75) :
Targeted, knock-out(9)
Targeted, other(6)
Gene trapped(59)
Transgenic(1)
| Homozygous null mutants fail to form a primitive streak, show placental defects and die at gastrulation. Hypomorphic mutants are defective in anterior-posterior, anterior-midline, and left-right body patterning, resulting in multiple organ defects. |
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Polymorphisms
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PCR(1)
SNPs within 2kb(9 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (139 records)
Data Summary:
Assays (25)
Results (184)
Tissues (40)
Images (88)
Theiler Stages: 4,6,7,8,9,10,11,12,13,19,20,21,22,23,24,25,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
6 |
|
20 |
| |
In situ reporter (knock in) |
2 |
|
36 |
| |
RNA in situ |
17 |
|
128 |
cDNA source data(5)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(28)
Genomic(3)
cDNA(7)
Primer pair(9)
Other(9)
Microarray probesets(3)
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Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001111 |
Transforming growth factor beta (TGFb), N-terminal |
| IPR001839 |
Transforming growth factor beta |
| IPR015615 |
Transforming growth factor-beta-related |
| IPR017948 |
Transforming growth factor beta, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:11389
Conlon FL et al.,
"A novel retrovirally induced embryonic lethal mutation in the mouse: assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral integration."
Development 1991 Apr;111(4):969-81
(Latest)
J:155112
Tsiairis CD et al.,
"An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry."
Curr Biol 2009 Dec 1;19(22):1912-7
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All references(177)
|
Other
accession IDs
|
MGD-MRK-12907, MGD-MRK-15051, MGI:98714
|
Analysis Tools
MGI BioMart
