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Mgl1 Gene Detail
 Symbol
Name
ID
Mgl1
macrophage galactose N-acetyl-galactosamine specific lectin 1
MGI:96975


Nomenclature History
Synonyms CD301a
Genetic Map
Chromosome 11
37.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr11:69980125-69984336 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Mgl1 ± 2 cM)
Protein SuperFamily: asialoglycoprotein receptor 1-like protein
TreeFam: TF352155
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006033 VEGA Gene Model | MGI Sequence Detail 4212 C57BL/6J ± Kb
transcript NM_010796 RefSeq | MGI Sequence Detail 1345 C57BL/6
polypeptide P49300 UniProt | EBI | MGI Sequence Detail 304 Not Applicable
For the selected sequences
All sequences(21)
Alleles
and
phenotypes
All alleles(1) : Targeted, knock-out(1)
Homozygotes for a targeted null mutation exhibit elevated red blood cell counts but appear to be otherwise normal.
Polymorphisms RFLP(1) SNPs within 2kb(62 from dbSNP Build 128)   SNPs within 2kb including multiple locations(72)
Gene Ontology
(GO)
classifications
All GO classifications(7)
Component integral to membrane, membrane...
Function binding, calcium ion binding...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
cDNA source data(25)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(27) Genomic(1) cDNA(26)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000000318
DoTS DT.101364327, DT.94258450
UniGene 252405
DFCI TC1585536
NIA Mouse Gene Index U012846
Entrez Gene 17312
VEGA Gene Model OTTMUSG00000006033
International Mouse Knockout Project Status Mgl1
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR002353 Type II antifreeze protein
IPR005640 Hepatic lectin, N-terminal
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:5439 Bannerman RM et al., "Hereditary disorders of the red cell in animals." Prog Hematol 1973;8():131-79
(Latest) J:144207 Saba K et al., "A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis." Am J Pathol 2009 Jan;174(1):144-52
All references(15)
Other
accession IDs
MGD-MRK-12220

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory