Symbol
Name
ID
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Synonyms
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lipopolysaccharide response, Lps, Rasl2-8
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(24)
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Alleles
and
phenotypes
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All alleles(8) :
Targeted, knock-out(1)
Spontaneous(5)
Chemically induced(2)
| Homozygotes for spontaneous or targeted mutations are hyporesponsive to bacterial lipopolysaccharide and more susceptible to infection by gram negative bacteria. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (3)
Phenotype Images (1)
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Polymorphisms
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PCR(2)
SNPs within 2kb(761 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (4 records)
cDNA source data(23)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(30)
Genomic(4)
cDNA(24)
Primer pair(2)
Microarray probesets(3)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:5087
Sultzer BM,
"Genetic control of leucocyte responses to endotoxin."
Nature 1968 Sep 21;219(160):1253-4
(Latest)
J:154197
Rodriguez S et al.,
"Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis."
Blood 2009 Nov 5;114(19):4064-76
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All references(680)
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Other
accession IDs
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MGD-MRK-11879, MGD-MRK-26042
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