Symbol
Name
ID
|
|
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STS
|
D6Mit14
|
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Synonyms
|
K-ras, Ki-ras, Kras-2, Kras2
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Genetic Map
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(36)
|
Alleles
and
phenotypes
|
All alleles(26) :
Targeted, knock-out(3)
Targeted, other(7)
Gene trapped(14)
Other(2)
| Mice homozygous for a null allele exhibit embryonic lethality, decreased fetal growth, pericardial edema, anemia, and liver hypoplasia. Mice heterozygous for various knock-in alleles exhibit increased tumorigenesis. |
Associated Human Diseases (3)
Alleles Annotated to Human Diseases (4)
|
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Polymorphisms
|
All PCR and RFLP(30) :
PCR(13)
RFLP(17)
SNPs within 2kb(187 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (12 records)
Data Summary:
Assays (12)
Results (145)
Tissues (50)
Images (11)
Theiler Stages: 19,21,22,23,25,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
11 |
|
99 |
| |
RT-PCR |
1 |
|
46 |
cDNA source data(14)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(44)
Genomic(10)
cDNA(17)
Primer pair(11)
Other(6)
Antibodies(7)
Microarray probesets(4)
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Other database
links
|
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:6226
Scolnick EM et al.,
"Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses."
Proc Natl Acad Sci U S A 1979 Oct;76(10):5355-9
(Latest)
J:155787
Yin X et al.,
"Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice."
Lung Cancer 2009 Feb;63(2):194-200
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All references(265)
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Other
accession IDs
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MGD-MRK-11597, MGD-MRK-11601, MGI:2141518
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Analysis Tools
MGI BioMart
