Symbol
Name
ID
|
|
|
STS
|
D11Nds9
|
|
Synonyms
|
Il-5
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(18)
|
Alleles
and
phenotypes
|
All alleles(5) :
Targeted, knock-out(5)
| Homozygotes for a targeted null mutation exhibit loss of normal airway hyperreactivity resulting from aeroallergen challenge, reduced numbers of CD5+ B cells in the peritoneal cavity at 2 weeks, and some altered responses to schistosomiasis infection. |
|
|
Polymorphisms
|
All PCR and RFLP(15) :
PCR(12)
RFLP(3)
SNPs within 2kb(37 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (6 records)
Data Summary:
Assays (4)
Results (37)
Tissues (19)
Images (1)
Theiler Stages: 21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
32 |
| |
Nuclease S1 |
1 |
|
5 |
cDNA source data(10)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(38)
Genomic(12)
cDNA(15)
Primer pair(8)
Other(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000186 |
Interleukin-5 |
| IPR009079 |
Four-helical cytokine-like, core |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:8504
Kinashi T et al.,
"Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II."
Nature 1986 Nov 6-12;324(6092):70-3
(Latest)
J:152787
McKee AS et al.,
"Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity."
J Immunol 2009 Oct 1;183(7):4403-14
|
All references(159)
|
Other
accession IDs
|
MGD-MRK-11356, MGD-MRK-11387
|
Analysis Tools
MGI BioMart
