Symbol
Name
ID
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Synonyms
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Il-4
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(27)
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Alleles and phenotypes
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All alleles(14) :
Targeted, knock-out(7)
Targeted, other(7)
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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All PCR and RFLP(9) :
PCR(4)
RFLP(5)
SNPs within 2kb(131 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (13 records)
Data Summary:
Assays (6)
Results (50)
Tissues (26)
Images (2)
Theiler Stages: 13,17,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
5 |
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44 |
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Nuclease S1 |
1 |
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6 |
cDNA source data(14)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(36)
Genomic(11)
cDNA(14)
Primer pair(6)
Other(5)
Microarray probesets(2)
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Other database links
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Protein domains
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| InterPro ID |
Description |
| IPR001325 |
Interleukin-4/interleukin-13 |
| IPR002354 |
Interleukin 4 |
| IPR009079 |
Four-helical cytokine-like, core |
| IPR018096 |
Interleukin-4/interleukin-13, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:39743
Howard M et al.,
"Identification of a T cell-derived b cell growth factor distinct from interleukin 2."
J Exp Med 1982 Mar 1;155(3):914-23
(Latest)
J:156317
Varin A et al.,
"Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion."
Blood 2010 Jan 14;115(2):353-62
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All references(648)
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Other accession IDs
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MGD-MRK-11355, MGD-MRK-11385
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