Symbol
Name
ID
|
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Synonyms
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1300007J06Rik, 2310022B03Rik, ALT, Gpt-1, Gpt1
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(21)
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Alleles
and
phenotypes
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All alleles(1) :
Targeted, knock-out(1)
| Electrophoretic variants are detected in C57BL/6, BALB/c and DBA/2 (a allele); in MA/J and NZB/Bl (b allele). M. m. molossinus and M. m. castaneus have either the b or c allele. In liver, GPT1 activity rises dramatically at 12-19 days to adult levels. |
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Polymorphisms
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SNPs within 2kb(26 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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cDNA source data(8)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(8)
cDNA(8)
Microarray probesets(2)
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Pathways
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR004839 |
Aminotransferase, class I/II |
| IPR015421 |
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 |
| IPR015422 |
Pyridoxal phosphate-dependent transferase, major region, subdomain 2 |
| IPR015424 |
Pyridoxal phosphate-dependent transferase, major domain |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:5384
Chen SH et al.,
"The genetics of glutamic-pyruvic transaminase in mice: inheritance, electrophoretic phenotypes, and postnatal changes."
Biochem Genet 1973 Sep;10(1):23-8
(Latest)
J:105553
Jadhao SB et al.,
"Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver."
Hepatology 2004 May;39(5):1297-302
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All references(22)
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Other
accession IDs
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MGD-MRK-10236, MGD-MRK-10237, MGI:1915263, MGI:1923532
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