Symbol
Name
ID
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Synonyms
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AMF, autocrine motility factor, Gpi-1, Gpi-1r, Gpi-1s, Gpi-1t, Gpi1-r, Gpi1-s, Gpi1-t, maturation factor, MF, neuroleukin, NK, NK/GPI, Org
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(49)
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Alleles
and
phenotypes
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All alleles(22) :
Gene trapped(8)
Spontaneous(1)
Chemically induced(9)
Radiation induced(1)
Other(4)
| Homozygotes for null mutations fail to develop beyond the egg cylinder stage and die by embryonic day 9.5. Homozygotes for a hypomorphic mutation exhibit nonspherocytic hemolytic anemia with hepatosplenomegaly. |
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Polymorphisms
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All PCR and RFLP(3) :
PCR(1)
RFLP(2)
SNPs within 2kb(209 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (4 records)
Data Summary:
Assays (2)
Results (132)
Tissues (101)
Images (19)
Theiler Stages: 22
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Assay Type |
Assays |
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Results |
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RNA in situ |
2 |
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132 |
cDNA source data(20)
External Resources:
GENSAT
GEO
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Molecular
reagents
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All nucleic(25)
Genomic(1)
cDNA(21)
Primer pair(2)
Other(1)
Microarray probesets(3)
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Pathways
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Other database
links
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| EC |
5.3.1.9 |
| Ensembl Gene Model |
ENSMUSG00000036427 |
| DoTS |
DT.101320425, DT.101358666, DT.101712464, DT.102553283, DT.102553284, DT.110980142, DT.495008 |
| PDB |
1U0E, 1U0F, 1U0G, 2CVP, 2CXN, 2CXO, 2CXP, 2CXQ, 2CXR, 2CXS, 2CXT, 2CXU |
| DFCI |
TC1573838, TC1587062, TC1602473 |
| NIA Mouse Gene Index |
U028425, U052539 |
| Entrez Gene |
14751 |
| VEGA Gene Model |
OTTMUSG00000008382 |
| International Mouse Knockout Project Status |
Gpi1 |
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Protein
domains
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| InterPro ID |
Description |
| IPR001672 |
Phosphoglucose isomerase (PGI) |
| IPR018189 |
Phosphoglucose isomerase, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:5134
Hutton JJ,
"Linkage analyses using biochemical variants in mice. I. Linkage of the hemoglobin beta-chain and glucosephosphate isomerase loci."
Biochem Genet 1969 Oct;3(5):507-15
(Latest)
J:138250
Repiso A et al.,
"Expression patterns in mouse embryos of neuroleukin/glucose-6-phosphate isomerase and autocrine motility factor receptor."
Anat Histol Embryol 2008 Oct;37(5):380-2
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All references(194)
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Other
accession IDs
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MGD-MRK-10227, MGD-MRK-10228, MGD-MRK-10229, MGD-MRK-10230, MGD-MRK-10231, MGD-MRK-10232, MGD-MRK-10233, MGD-MRK-10234, MGD-MRK-13047, MGI:95798, MGI:95799, MGI:95800
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