Symbol
Name
ID
|
|
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Synonyms
|
Gdh-X, Glud
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(31)
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Alleles
and
phenotypes
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All alleles(46) :
Targeted, other(1)
Gene trapped(45)
| Mice homozygous for a conditionally allele activated in beta cells exhibit reduced glucose-stimulated insulin secretion and disorganization of pancreatic islets. |
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Polymorphisms
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RFLP(9)
SNPs within 2kb(171 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (1 records)
Data Summary:
Assays (1)
Results (93)
Tissues (93)
Images (14)
Theiler Stages: 22
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
1 |
|
93 |
cDNA source data(11)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(17)
Genomic(1)
cDNA(14)
Primer pair(1)
Other(1)
Microarray probesets(3)
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Pathways
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR006095 |
Glutamate/phenylalanine/leucine/valine dehydrogenase |
| IPR006096 |
Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal |
| IPR006097 |
Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain |
| IPR016040 |
NAD(P)-binding domain |
Graphical View
of Protein Domain Structure
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|
References
|
(Earliest)
J:8729
Banner C et al.,
"Isolation of a human brain cDNA for glutamate dehydrogenase."
J Neurochem 1987 Jul;49(1):246-52
(Latest)
J:145558
Carobbio S et al.,
"Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis."
J Biol Chem 2009 Jan 9;284(2):921-9
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All references(29)
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Other
accession IDs
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MGD-MRK-10046, MGD-MRK-10136, MGD-MRK-10139, MGI:2145599
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