Symbol
Name
ID
|
|
|
Synonyms
|
Gata-3
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(37)
|
Alleles
and
phenotypes
|
All alleles(12) :
Targeted, knock-out(4)
Targeted, other(7)
Gene trapped(1)
| Homozygous inactivation is embryonic lethal. Embryos exhibit growth retardation, deformities of the brain, spinal cord and inner ear, and impaired fetal liver hematopoiesis. T cell development is impaired when the locus is conditionally inactivated during this process. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
SNPs within 2kb(104 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (96 records)
Data Summary:
Assays (24)
Results (329)
Tissues (261)
Images (101)
Theiler Stages: 2,3,4,5,12,13,14,15,16,17,18,19,20,21,22,23,24,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
31 |
| |
In situ reporter (knock in) |
1 |
|
4 |
| |
RNA in situ |
13 |
|
258 |
| |
Immunohistochemistry |
5 |
|
36 |
cDNA source data(78)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(96)
Genomic(7)
cDNA(80)
Primer pair(6)
Other(3)
Antibodies(2)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000679 |
Zinc finger, GATA-type |
| IPR013088 |
Zinc finger, NHR/GATA-type |
| IPR016374 |
Transcription factor, GATA-1/2/3 |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:699
Zon LI et al.,
"GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene."
J Biol Chem 1991 Dec 5;266(34):22948-53
(Latest)
J:153192
Morikawa Y et al.,
"Characterization of Foxp2-expressing cells in the developing spinal cord."
Neuroscience 2009 Sep 15;162(4):1150-62
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All references(150)
|
Other
accession IDs
|
MGD-MRK-10000, MGD-MRK-10004
|
