Symbol
Name
ID
|
|
|
STS
|
D12Mit95
|
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Synonyms
|
c-fos, D12Rfj1
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Genetic Map
|
|
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Sequence Map
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Mammalian
homology
|
|
|
Sequences
|
All sequences(20)
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Alleles
and
phenotypes
|
All alleles(5) :
Targeted, knock-out(2)
Targeted, other(3)
| Null mutants are growth-retarded, most dying perinatally. Survivors have osteopetrosis and abnormal tooth eruption, gametogenesis, hemopoiesis, behavior and photoreceptor apoptosis. Hippocampal-specific mutants have seizures and highly excitable neurons. |
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Polymorphisms
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All PCR and RFLP(13) :
PCR(2)
RFLP(11)
SNPs within 2kb(35 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (35 records)
Data Summary:
Assays (9)
Results (163)
Tissues (101)
Images (8)
Theiler Stages: 2,3,4,5,15,17,20,21,22,23,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
117 |
| |
RNA in situ |
4 |
|
46 |
cDNA source data(6)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(30)
Genomic(10)
cDNA(10)
Primer pair(7)
Other(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000837 |
Fos transforming protein |
| IPR004827 |
Basic-leucine zipper (bZIP) transcription factor |
| IPR011616 |
bZIP transcription factor, bZIP-1 |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:6867
Muller R et al.,
"Differential expression of cellular oncogenes during pre- and postnatal development of the mouse."
Nature 1982 Oct 14;299(5884):640-4
(Latest)
J:155398
Hanada R et al.,
"Central control of fever and female body temperature by RANKL/RANK."
Nature 2009 Nov 26;462(7272):505-9
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All references(253)
|
Other
accession IDs
|
MGD-MRK-19548, MGD-MRK-9866
|
Analysis Tools
MGI BioMart
