Symbol
Name
ID
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Synonyms
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Fib-1
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(33)
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Alleles
and
phenotypes
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All alleles(5) :
Targeted, knock-out(3)
Targeted, other(1)
Spontaneous(1)
| Lethality among homozygotes for spontaneous and targeted mutations ranges from embryonic death to death around 4 months. Abnormalities include vascular defects, excess bone growth, connective tissue hyperplasia, and lung emphysema. |
Associated Human Diseases (4)
Alleles Annotated to Human Diseases (5)
Phenotype Images (6)
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Polymorphisms
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RFLP(7)
SNPs within 2kb(1289 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
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Literature Summary: (12 records)
Data Summary:
Assays (5)
Results (48)
Tissues (11)
Images (1)
Theiler Stages: 20,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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8 |
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RT-PCR |
2 |
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16 |
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Northern blot |
2 |
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24 |
cDNA source data(31)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
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All nucleic(44)
Genomic(5)
cDNA(36)
Primer pair(2)
Other(1)
Antibodies(1)
Microarray probesets(3)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:27521
Green MC et al.,
"Tight skin (Tsk)"
Mouse News Lett 1973;48():34
(Latest)
J:149984
Podowski M et al.,
"Complex integration of matrix, oxidative stress, and apoptosis in genetic emphysema."
Am J Pathol 2009 Jul;175(1):84-96
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All references(124)
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Other
accession IDs
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MGD-MRK-15276, MGD-MRK-9717, MGI:2138999, MGI:98850
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