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Fabp1 Gene Detail
 Symbol
Name
ID
Fabp1
fatty acid binding protein 1, liver
MGI:95479

Nomenclature History
Synonyms Fabpl, L-FABP, MGC:13855
Genetic Map
Chromosome 6
30.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr6:71149821-71155017 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Fabp1 ± 2 cM)
Protein SuperFamily: lipid binding protein, FABP type
TreeFam: TF330348
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000023123 VEGA Gene Model | MGI Sequence Detail 5197 C57BL/6J ± Kb
transcript NM_017399 RefSeq | MGI Sequence Detail 492 C57BL/6
polypeptide P12710 UniProt | EBI | MGI Sequence Detail 127 Not Applicable
For the selected sequences
All sequences(13)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(1)
Mice homozygous for a disruption in this gene do not show any obvious morphological, behavioral, or reproductive abnormalities. Changes may be observed in lipid composition, lipid binding, or levels of lipid binding proteins.
Polymorphisms RFLP(4) SNPs within 2kb(39 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process transport
Component cytoplasm, nucleus...
Function binding, chromatin binding...
External Resources: FuncBase
Expression Literature Summary: (15 records)
Data Summary: Assays (2)    Results (5)    Tissues (4)
Theiler Stages: 21,23,25
  Assay Type Assays   Results
      RT-PCR 2   5
cDNA source data(120)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(124) cDNA(122) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000054422
DoTS DT.495164
Consensus CDS Project CCDS20226.1
UniGene 22126
DFCI TC1575046
NIA Mouse Gene Index U007013
Entrez Gene 14080
VEGA Gene Model OTTMUSG00000023123
International Mouse Knockout Project Status Fabp1
Protein
domains
InterPro ID Description
IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding protein
IPR011038 Calycin-like
IPR012674 Calycin
Graphical View of Protein Domain Structure
References
(Earliest) J:8932 Sweetser DA et al., "The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships." J Biol Chem 1987 Nov 25;262(33):16060-71
(Latest) J:155905 Martin GG et al., "Hepatic phenotype of liver fatty acid binding protein gene-ablated mice." Am J Physiol Gastrointest Liver Physiol 2009 Dec;297(6):G1053-65
All references(45)
Other
accession IDs 		MGD-MRK-9706
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory