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Fabp3 Gene Detail
 Symbol
Name
ID
Fabp3
fatty acid binding protein 3, muscle and heart
MGI:95476


Nomenclature History
Synonyms Fabp3, Fabph-1, Fabph-4, Fabph1, Fabph4, H-FABP, Mdgi
Genetic Map
Chromosome 4
61.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 8)

Sequence Map
Chr4:129985839-129992707 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Fabp3 ± 2 cM)
Protein SuperFamily: lipid binding protein, FABP type
TreeFam: TF316894
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000009558 VEGA Gene Model | MGI Sequence Detail 6869 C57BL/6J ± Kb
transcript NM_010174 RefSeq | MGI Sequence Detail 669 BALB/c
polypeptide P11404 UniProt | EBI | MGI Sequence Detail 133 Not Applicable
For the selected sequences
All sequences(24)
Alleles
and
phenotypes
All alleles(17) : Targeted, knock-out(2) Gene trapped(15)
Inactivation of this locus results in impaired fatty acid utilization. Homozygous null mice show exercise intolerance and cardiac hypertrophy.
Polymorphisms RFLP(3) SNPs within 2kb(84 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process phosphatidylcholine biosynthetic process, transport...
Component cytoplasm
Function binding, lipid binding...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (4)    Results (95)    Tissues (47)    Images (2)
Theiler Stages: 22,23,28
  Assay Type Assays   Results
      RT-PCR 3   94
      RNA in situ 1   1
cDNA source data(10)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(18) Genomic(2) cDNA(11) Primer pair(5)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000028773
DoTS DT.537486, DT.87057194
Consensus CDS Project CCDS18709.1
DFCI TC1571991, TC1636506
NIA Mouse Gene Index U004883, U060082
Entrez Gene 14077
VEGA Gene Model OTTMUSG00000009558
International Mouse Knockout Project Status Fabp3
Protein
domains
InterPro ID Description
IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding protein
IPR011038 Calycin-like
IPR012674 Calycin
Graphical View of Protein Domain Structure
References
(Earliest) J:8761 Heuckeroth RO et al., "Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein." J Biol Chem 1987 Jul 15;262(20):9709-17
(Latest) J:148797 Zheng J et al., "Identifying components of the hair-cell interactome involved in cochlear amplification." BMC Genomics 2009;10():127
All references(32)
Other
accession IDs
MGD-MRK-35894, MGD-MRK-9697, MGD-MRK-9700, MGD-MRK-9701, MGD-MRK-9704, MGI:95477

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory