Symbol
Name
ID
|
Dci
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase)
MGI:94871
|
Nomenclature History
|
|
|
Synonyms
|
eci
|
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Genetic Map
|
|
Chromosome 17
|
cytoband A3.3
|
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Mapping data(
3)
|
|
|
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Sequence Map
|
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Mammalian
homology
|
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Sequences
|
All sequences(22)
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Alleles
and
phenotypes
|
All alleles(8) :
Targeted, knock-out(1)
Gene trapped(7)
| Mice homozygous for disruption of this gene are normal until stressed. Starvation results in increased accumulation of triglycerides and unsaturated fatty acids in the liver and kidney. Secretion of fatty acid metabolites in the urine is greatly increased. |
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Polymorphisms
|
SNPs within 2kb(41 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
cDNA source data(80)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(84)
Genomic(2)
cDNA(81)
Primer pair(1)
Microarray probesets(2)
|
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Pathways
|
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR001753 |
Crotonase, core |
| IPR018376 |
Enoyl-CoA hydratase/isomerase, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:15191
Stoffel W et al.,
"Molecular cloning and gene organization of the mouse mitochondrial 3,2-trans-enoyl-CoA isomerase."
FEBS Lett 1993 Oct 25;333(1-2):119-22
(Latest)
J:151002
Pagliarini DJ et al.,
"A mitochondrial protein compendium elucidates complex I disease biology."
Cell 2008 Jul 11;134(1):112-23
|
All references(10)
|
Other
accession IDs
|
MGD-MRK-8810
|
Analysis Tools
MGI BioMart