About   Help   FAQ
Acsl6 Gene Detail
 Symbol
Name
ID
Acsl6
acyl-CoA synthetase long-chain family member 6
MGI:894291


Nomenclature History
Synonyms A330035H04Rik, Facl6, Lacsl
Genetic Map
Chromosome 11
29.35 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr11:54117300-54178258 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Acsl6 ± 2 cM)
TreeFam: TF313877
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000005668 VEGA Gene Model | MGI Sequence Detail 60959 C57BL/6J ± Kb
transcript NM_001033599 RefSeq | MGI Sequence Detail 2767 C57BL/6
polypeptide Q91WC3 UniProt | EBI | MGI Sequence Detail 697 Not Applicable
For the selected sequences
All sequences(58)
Alleles
and
phenotypes
All alleles(1) : Targeted, other(1)
Polymorphisms SNPs within 2kb(381 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process fatty acid metabolic process, lipid metabolic process...
Component endoplasmic reticulum, integral to membrane...
Function ATP binding, catalytic activity...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (6)    Tissues (2)
Theiler Stages: 24,28
  Assay Type Assays   Results
      RT-PCR 1   6
cDNA source data(33)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(40) Genomic(4) cDNA(33) Primer pair(2) Other(1)
Microarray probesets(2)
Pathways
fatty acid β-oxidation I
fatty acid β-oxidation II (core pathway)
fatty acid activation
Other database
links
EC 6.2.1.3
Ensembl Gene Model ENSMUSG00000020333
DoTS DT.101215216, DT.101725120, DT.110522064, DT.40142886, DT.87027723, DT.91398478, DT.97362567
Consensus CDS Project CCDS24694.1, CCDS24695.1, CCDS24696.1, CCDS24697.1
UniGene 267478
DFCI TC1579087, TC1592984, TC1593543, TC1596879, TC1598000, TC1601639
Entrez Gene 216739
VEGA Gene Model OTTMUSG00000005668
International Mouse Knockout Project Status Acsl6
Protein
domains
InterPro ID Description
IPR000873 AMP-dependent synthetase/ligase
IPR020845 AMP-binding, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:40314 Frazer KA et al., "Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region." Genome Res 1997 May;7(5):495-512
(Latest) J:120282 de Jong H et al., "Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart." Biochim Biophys Acta 2007 Jan;1771(1):75-82
All references(9)
Other
accession IDs
MGI:2144490, MGI:2444956

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/06/2010
MGI_4.32
Web browser compatibility
The Jackson Laboratory