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Bche Gene Detail
 Symbol
Name
ID
Bche
butyrylcholinesterase
MGI:894278


Nomenclature History
Synonyms C730038G20Rik
Genetic Map
Chromosome 3
cytoband E3
 
Mapping data( 2)
Sequence Map
Chr3:73439730-73512337 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: esterase, acetylcholinesterase type
TreeFam: TF315470
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000026601 VEGA Gene Model | MGI Sequence Detail 72608 C57BL/6J ± Kb
transcript NM_009738 RefSeq | MGI Sequence Detail 6209 C57BL/6
polypeptide Q03311 UniProt | EBI | MGI Sequence Detail 603 Not Applicable
For the selected sequences
All sequences(18)
Alleles
and
phenotypes
All alleles(1) : Targeted, knock-out(1)
Mice homozygous for a targeted null mutation do not exhibit any overt abnormalities.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms SNPs within 2kb(286 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process biological_process
Component endoplasmic reticulum, membrane...
Function carboxylesterase activity, cholinesterase activity...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
cDNA source data(6)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(7) Genomic(1) cDNA(6)
Microarray probesets(2)
Other database
links
EC 3.1.1.8
Ensembl Gene Model ENSMUSG00000027792
DoTS DT.40183821, DT.91290694
NIA Mouse Gene Index U024155
Entrez Gene 12038
VEGA Gene Model OTTMUSG00000026601
International Mouse Knockout Project Status Bche
Protein
domains
InterPro ID Description
IPR000997 Cholinesterase
IPR002018 Carboxylesterase, type B
IPR014788 Acetylcholinesterase, tetramerisation
IPR019819 Carboxylesterase type B, conserved site
IPR019826 Carboxylesterase type B, active site
Graphical View of Protein Domain Structure
References
(Earliest) J:41300 Rachinsky TL et al., "Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species." Neuron 1990 Sep;5(3):317-27
(Latest) J:148458 Duysen EG et al., "The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease." Expert Opin Drug Metab Toxicol 2009 May;5(5):523-8
All references(7)
Other
accession IDs
MGI:2445138

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory