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Cycs Gene Detail
 Symbol
Name
ID
Cycs
cytochrome c, somatic
MGI:88578

Nomenclature History
Genetic Map
Chromosome 6
23.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr6:50512562-50516537 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; horse; rabbit, European; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cycs ± 2 cM)
Protein SuperFamily: cytochrome c/cytochrome c2
TreeFam: TF300226
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000034264 VEGA Gene Model | MGI Sequence Detail 3976 C57BL/6J ± Kb
transcript NM_007808 RefSeq | MGI Sequence Detail 3059 C57BL/6
polypeptide P62897 UniProt | EBI | MGI Sequence Detail 105 Not Applicable
For the selected sequences
All sequences(25)
Alleles
and
phenotypes 		All alleles(4) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(2)
Mice homozygous for a targeted mutation die at midgestation. By E8.5, homozygous null embryos exhibit a strikingly reduced size and are developmentally retarded.
Polymorphisms RFLP(2) SNPs within 2kb(32 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process activation of caspase activity by cytochrome c, apoptosis...
Component cytosol, mitochondrion...
Function electron carrier activity, heme binding...
External Resources: FuncBase
Expression Literature Summary: (3 records)
cDNA source data(231)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(233) Genomic(2) cDNA(231)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000063694
DoTS DT.101277138, DT.102540369, DT.496226
Consensus CDS Project CCDS20131.1
UniGene 35389
DFCI TC1573177
Entrez Gene 13063
VEGA Gene Model OTTMUSG00000034264
International Mouse Knockout Project Status Cycs
Protein
domains
InterPro ID Description
IPR002327 Cytochrome c, class IA/ IB
IPR003088 Cytochrome c, class I
IPR009056 Cytochrome c, monohaem
Graphical View of Protein Domain Structure
References
(Earliest) J:38101 Limbach KJ et al., "Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes." Nucleic Acids Res 1985 Jan 25;13(2):617-30
(Latest) J:147780 Vempati UD et al., "Lack of cytochrome c in mouse fibroblasts disrupts assembly/stability of respiratory complexes I and IV." J Biol Chem 2009 Feb 13;284(7):4383-91
All references(32)
Other
accession IDs 		MGD-MRK-2287
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory