Symbol
Name
ID
|
|
|
STS
|
D6Mit138
|
|
Synonyms
|
Col1a-2, Cola-2, Cola2
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(58)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, other(1)
Gene trapped(1)
Spontaneous(1)
| Animals homozygous for a mutation in this gene exhibit reduced body size, reduced bone density and cortical bone thickness, fractured and deformed long bones, dorsal kyphosis, and droopy wrists. Older mutants develop an abnormal gait. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
Phenotype Images (2)
|
|
Polymorphisms
|
RFLP(4)
SNPs within 2kb(36 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (62 records)
Data Summary:
Assays (7)
Results (32)
Tissues (26)
Images (6)
Theiler Stages: 16,19,20,21,22,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
12 |
| |
RNA in situ |
3 |
|
18 |
| |
Northern blot |
1 |
|
2 |
cDNA source data(1262)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(1278)
Genomic(5)
cDNA(1267)
Primer pair(3)
Other(3)
Microarray probesets(3)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000885 |
Fibrillar collagen, C-terminal |
| IPR008160 |
Collagen triple helix repeat |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:7086
Shupp Byrne DE et al.,
"Assignment of the genes for mouse type I procollagen to chromosome 16 using mouse fibroblast-Chinese hamster somatic cell hybrids."
Somatic Cell Genet 1983 May;9(3):313-31
(Latest)
J:151466
Gamer LW et al.,
"Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures."
Dev Dyn 2009 Aug 3;238(9):2374-2381
|
All references(142)
|
Other
accession IDs
|
MGD-MRK-13027, MGD-MRK-2060, MGD-MRK-2088, MGD-MRK-2090, MGI:2141374, MGI:2141395
|
