Symbol
Name
ID
|
|
|
Synonyms
|
Chx10, Hox-10, Hox10
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(19)
|
Alleles
and
phenotypes
|
All alleles(7) :
Targeted, other(4)
Spontaneous(3)
| Homozygotes for spontaneous mutations exhibit microphthalmia, lack of retinal intercellular channels, and agenesis of the optic nerve. Homozygotes for one mutant allele also have a germ cell maturation defect with sterility in both sexes. |
Phenotype Images (1)
|
|
Polymorphisms
|
RFLP(1)
SNPs within 2kb(113 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (119 records)
Data Summary:
Assays (14)
Results (87)
Tissues (55)
Images (50)
Theiler Stages: 17,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RNA in situ |
10 |
|
73 |
| |
Immunohistochemistry |
4 |
|
14 |
cDNA source data(44)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(52)
Genomic(4)
cDNA(46)
Other(2)
Antibodies(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:307
TRUSLOVE GM,
"A gene causing ocular retardation in the mouse."
J Embryol Exp Morphol 1962 Dec;10():652-60
(Latest)
J:153566
Fujimura N et al.,
"Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium."
Dev Biol 2009 Oct 1;334(1):31-45
|
All references(159)
|
Other
accession IDs
|
MGD-MRK-10826, MGD-MRK-13044, MGD-MRK-1983
|
