Symbol
Name
ID
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Synonyms
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B230380D24Rik
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(3)
Targeted, other(3)
| Homozygous mutation of this gene results in hyperinnervation of motor neurons, abnormal morphology and patterning of neuromuscular synapses, and perinatal lethality. Mutant fetuses at E18.5 exhibit a hunched position, reduced body length, and carpoptosis (drop wrist). |
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Polymorphisms
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SNPs within 2kb(258 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (94 records)
Data Summary:
Assays (8)
Results (130)
Tissues (103)
Images (16)
Theiler Stages: 15,17,21,22,23,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
4 |
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27 |
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RNA in situ |
4 |
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103 |
cDNA source data(16)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(29)
Genomic(8)
cDNA(17)
Primer pair(3)
Other(1)
Microarray probesets(1)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000542 |
Acyltransferase ChoActase/COT/CPT |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:10493
Ishii K et al.,
"Complementary DNAs for choline acetyltransferase from spinal cords of rat and mouse: nucleotide sequences, expression in mammalian cells, and in situ hybridization."
Brain Res Mol Brain Res 1990 Feb;7(2):151-9
(Latest)
J:153908
de Castro BM et al.,
"The vesicular acetylcholine transporter is required for neuromuscular development and function."
Mol Cell Biol 2009 Oct;29(19):5238-50
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All references(130)
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Other
accession IDs
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MGD-MRK-1967, MGI:2443404
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