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F5 Gene Detail
 Symbol
Name
ID
F5
coagulation factor V
MGI:88382


Nomenclature History
Synonyms Cf-5, Cf5
Genetic Map
Chromosome 1
86.6 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr1:166081990-166150405 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human F5 ± 2 cM)
Protein SuperFamily: coagulation factor V-like protein
TreeFam: TF329807
Sequences
Representative Sequences Length Strain/Species Flank
genomic 14067 NCBI Gene Model | MGI Sequence Detail 68416 C57BL/6J ± Kb
transcript NM_007976 RefSeq | MGI Sequence Detail 7406 C57BL/6
polypeptide O88783 UniProt | EBI | MGI Sequence Detail 2183 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms RFLP(1) SNPs within 2kb(431 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(13)
Process blood circulation, blood coagulation...
Component extracellular region, extracellular space...
Function calcium ion binding, copper ion binding...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (9)    Tissues (9)
Theiler Stages: 11,13,15,17,19,20,21,22,28
  Assay Type Assays   Results
      RT-PCR 1   9
cDNA source data(44)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(48) Genomic(2) cDNA(45) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000026579
DoTS DT.496636
UniGene 12900
DFCI TC1582458, TC1609309, TC1700496
NIA Mouse Gene Index U001016
Entrez Gene 14067
International Mouse Knockout Project Status F5
Protein
domains
InterPro ID Description
IPR000421 Coagulation factor 5/8 type, C-terminal
IPR002355 Multicopper oxidase, copper-binding site
IPR008972 Cupredoxin
IPR008979 Galactose-binding domain-like
IPR009271 Coagulation factor V LSPD
IPR011707 Multicopper oxidase, type 3
Graphical View of Protein Domain Structure
References
(Earliest) J:9416 Dahlback B et al., "Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat." Somat Cell Mol Genet 1988 Sep;14(5):509-14
(Latest) J:149496 Kisucka J et al., "Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis." Blood 2009 Jun 4;113(23):6015-22
All references(24)
Other
accession IDs
MGD-MRK-1948, MGD-MRK-1954, MGI:2138166

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory