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Cd40lg Gene Detail
 Symbol
Name
ID
Cd40lg
CD40 ligand
MGI:88337

Nomenclature History
Synonyms CD154, Cd40L, gp39, HIGM1, IMD3, Ly-62, T-BAM, Tnfsf5
Genetic Map
Chromosome X
18.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
ChrX:54465320-54477219 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cd40lg ± 2 cM)
Protein SuperFamily: tumor necrosis factor ligand superfamily protein, CD40 ligand type
TreeFam: TF332169
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017791 VEGA Gene Model | MGI Sequence Detail 11900 C57BL/6J ± Kb
transcript NM_011616 RefSeq | MGI Sequence Detail 1250 -
polypeptide P27548 UniProt | EBI | MGI Sequence Detail 260 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(2)
Polymorphisms SNPs within 2kb(87 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process B cell differentiation, immune response...
Component extracellular region, extracellular space...
Function cytokine activity, tumor necrosis factor receptor binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
cDNA source data(2)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(5) Genomic(3) cDNA(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000031132
DoTS DT.87038738
Consensus CDS Project CCDS30152.1
UniGene 4861
PDB 1CDA
DFCI TC1594456
NIA Mouse Gene Index U019872
Entrez Gene 21947
VEGA Gene Model OTTMUSG00000017791
International Mouse Knockout Project Status Cd40lg
Protein
domains
InterPro ID Description
IPR003263 Tumor Necrosis Factor, TNF-5
IPR006052 Tumor Necrosis Factor
IPR008983 Tumour necrosis factor-like
Graphical View of Protein Domain Structure
References
(Earliest) J:831 Armitage RJ et al., "Molecular and biological characterization of a murine ligand for CD40." Nature 1992 May 7;357(6373):80-2
(Latest) J:151852 Kuraoka M et al., "Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome." J Immunol 2009 Sep 1;183(5):3237-48
All references(206)
Other
accession IDs 		MGD-MRK-12004, MGD-MRK-12047, MGD-MRK-1860
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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