Symbol
Name
ID
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Synonyms
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4930549J05Rik, CD3-eta, CD3-zeta, CD3-zeta/eta, Cd3h, Cd3z, CD3zeta, T3z, TCRk, Tcrz
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(38)
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Alleles
and
phenotypes
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All alleles(7) :
Targeted, knock-out(5)
Targeted, other(2)
| Homozygotes for targeted null mutations exhibit greatly reduced numbers of CD4+CD8+ cells, and near absence of CD4+CD8-, CD4-CD8+ cells, and TCR expression in the thymus, but the presence of single positive T cells in lymph nodes. |
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Polymorphisms
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RFLP(7)
SNPs within 2kb(676 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (3 records)
Data Summary:
Assays (1)
Results (46)
Tissues (45)
Images (1)
Theiler Stages: 23,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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46 |
cDNA source data(22)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(31)
Genomic(6)
cDNA(24)
Primer pair(1)
Microarray probesets(5)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR003110 |
Phosphorylated immunoreceptor signaling ITAM |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:9058
Weissman AM et al.,
"Molecular cloning of the zeta chain of the T cell antigen receptor."
Science 1988 Feb 26;239(4843):1018-21
(Latest)
J:136685
Perruche S et al.,
"CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells."
Nat Med 2008 May;14(5):528-35
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All references(104)
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Other
accession IDs
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MGD-MRK-14699, MGD-MRK-14930, MGD-MRK-1855, MGD-MRK-1856, MGD-MRK-1857, MGI:1922598, MGI:2138612
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Analysis Tools
MGI BioMart
