Symbol
Name
ID
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Synonyms
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Ctg-3, Ctg3, T3g
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(30)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(3)
Targeted, other(1)
Gene trapped(2)
| Mice homozygous for a knock-out allele exhibit decreased thymocyte number and T cell response. |
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Polymorphisms
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RFLP(2)
SNPs within 2kb(92 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (1 records)
cDNA source data(30)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(40)
Genomic(9)
cDNA(31)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
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| InterPro ID |
Description |
| IPR003110 |
Phosphorylated immunoreceptor signaling ITAM |
| IPR003598 |
Immunoglobulin subtype 2 |
| IPR013783 |
Immunoglobulin-like fold |
| IPR015484 |
CD3 protein, gamma/delta subunit |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:8651
Gold DP et al.,
"The gene encoding the epsilon subunit of the T3/T-cell receptor complex maps to chromosome 11 in humans and to chromosome 9 in mice."
Proc Natl Acad Sci U S A 1987 Mar;84(6):1664-8
(Latest)
J:155472
Brodeur JF et al.,
"Expression of fully assembled TCR-CD3 complex on double positive thymocytes: synergistic role for the PRS and ER retention motifs in the intra-cytoplasmic tail of CD3epsilon."
Int Immunol 2009 Dec;21(12):1317-27
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All references(41)
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Other
accession IDs
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MGD-MRK-14698, MGD-MRK-1854, MGD-MRK-2212, MGD-MRK-2213
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Analysis Tools
MGI BioMart
