Symbol
Name
ID
|
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STS
|
D9Mit23
|
|
Synonyms
|
T3d
|
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
|
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Sequences
|
All sequences(27)
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Alleles
and
phenotypes
|
All alleles(7) :
Targeted, knock-out(2)
Gene trapped(5)
| Homozygotes for targeted null mutations exhibit impaired early thymic development, small numbers of peripheral TCR-alpha/beta+ T cells, and failure of T lymphocyte transition from double-positive to single-positive developmental stages. |
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Polymorphisms
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All PCR and RFLP(4) :
PCR(3)
RFLP(1)
SNPs within 2kb(42 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (1 records)
cDNA source data(15)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(26)
Genomic(9)
cDNA(15)
Primer pair(2)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR003110 |
Phosphorylated immunoreceptor signaling ITAM |
| IPR013783 |
Immunoglobulin-like fold |
| IPR015484 |
CD3 protein, gamma/delta subunit |
| IPR015485 |
CD3 signaling complex delta subunit |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:7832
van den Elsen P et al.,
"Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein."
Nature 1985 Apr 11-17;314(6011):542-4
(Latest)
J:155472
Brodeur JF et al.,
"Expression of fully assembled TCR-CD3 complex on double positive thymocytes: synergistic role for the PRS and ER retention motifs in the intra-cytoplasmic tail of CD3epsilon."
Int Immunol 2009 Dec;21(12):1317-27
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All references(36)
|
Other
accession IDs
|
MGD-MRK-14696, MGD-MRK-1852
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Analysis Tools
MGI BioMart
