Symbol
Name
ID
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(22)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(4)
Targeted, other(2)
| Homozygous mutation of this gene results in impairment of some T cell responses and decreased basal immunoglobulin levels. Mutant animals have reduced T helper cell activity and impaired T cell response to lectins, but cytotoxic T cells can still be induced. |
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Polymorphisms
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RFLP(2)
SNPs within 2kb(293 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (1 records)
cDNA source data(33)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(37)
Genomic(1)
cDNA(36)
Microarray probesets(2)
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Other database
links
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Protein
domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:23361
Gross JA et al.,
"The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression."
J Immunol 1990 Apr 15;144(8):3201-10
(Latest)
J:156498
Obar JJ et al.,
"CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses."
Proc Natl Acad Sci U S A 2010 Jan 5;107(1):193-8
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All references(299)
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Other
accession IDs
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MGD-MRK-1845
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Analysis Tools
MGI BioMart
