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Car1 Gene Detail
 Symbol
Name
ID
Car1
carbonic anhydrase 1
MGI:88268


Nomenclature History
Synonyms CA I, Car-1
Genetic Map
Chromosome 3
10.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 13)

Sequence Map
Chr3:14766217-14778459 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Car1 ± 2 cM)
Protein SuperFamily: carbonate dehydratase
TreeFam: TF316425
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000026455 VEGA Gene Model | MGI Sequence Detail 12243 C57BL/6J ± Kb
transcript NM_009799 RefSeq | MGI Sequence Detail 1196 C57BL/6
polypeptide P13634 UniProt | EBI | MGI Sequence Detail 261 Not Applicable
For the selected sequences
All sequences(36)
Alleles
and
phenotypes
This locus controls electrophoretic variation in red blood cells. The a allele determines a slow migrating form in C57BL/6, C3H/He and other strains; the b allele determines a fast form in IS/Cam, WB/Re, SM, M. m. castaneus and M. m. molossinus.
Polymorphisms SNPs within 2kb(156 from dbSNP Build 128)   SNPs within 2kb including multiple locations(176)
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process one-carbon metabolic process
Component cytoplasm
Function carbonate dehydratase activity, lyase activity...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (2)    Results (96)    Tissues (95)    Images (10)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 2   96
cDNA source data(101)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(105) Genomic(3) cDNA(101) Primer pair(1)
Microarray probesets(2)
Other database
links
EC 4.2.1.1
Ensembl Gene Model ENSMUSG00000027556
DoTS DT.101385200, DT.494947
UniGene 273195
DFCI TC1574839
Entrez Gene 12346
VEGA Gene Model OTTMUSG00000026455
International Mouse Knockout Project Status Car1
Protein
domains
InterPro ID Description
IPR001148 Carbonic anhydrase, alpha-class, catalytic domain
IPR018338 Carbonic anhydrase, alpha-class, conserved site
IPR018442 Carbonic anhydrase, CA-I
Graphical View of Protein Domain Structure
References
(Earliest) J:13639 Biddle FG, "Pro-1." Mouse News Lett 1974;50():3
(Latest) J:125993 Cankaya M et al., "An analysis of expression patterns of genes encoding proteins with catalytic activities." BMC Genomics 2007;8():232
All references(25)
Other
accession IDs
MGD-MRK-1759, MGD-MRK-1762, MGI:2140006

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory