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Adss Gene Detail
 Symbol
Name
ID
Adss
adenylosuccinate synthetase, non muscle
MGI:87948

Nomenclature History
Synonyms AS
Genetic Map
Chromosome 1
Syntenic
 
Mapping data( 3)
Sequence Map
Chr1:179693309-179726640 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: adenylosuccinate synthase
TreeFam: TF300486
Sequences
Representative Sequences Length Strain/Species Flank
genomic 11566 NCBI Gene Model | MGI Sequence Detail 33332 C57BL/6J ± Kb
transcript NM_007422 RefSeq | MGI Sequence Detail 2553 C57BL/6
polypeptide P46664 UniProt | EBI | MGI Sequence Detail 456 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes 		All alleles(9) : Gene trapped(9)
Polymorphisms SNPs within 2kb(212 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(11)
Process AMP biosynthetic process, purine nucleotide biosynthetic process...
Component cytoplasm
Function adenylosuccinate synthase activity, GTP binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: MouseFunc
Expression cDNA source data(136)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents 		All nucleic(137) cDNA(137)
Microarray probesets(2)
Pathways
salvage pathways of purine nucleosides I
Other database
links
EC 6.3.4.4
Ensembl Gene Model ENSMUSG00000015961
DoTS DT.101722074, DT.101734733, DT.534797
UniGene 338021
DFCI TC1574042, TC1590609, TC1598046
NIA Mouse Gene Index U022123
Entrez Gene 11566
International Mouse Knockout Project Status Adss
Protein
domains
InterPro ID Description
IPR001114 Adenylosuccinate synthetase
IPR018220 Adenylosuccinate synthase, active site
Graphical View of Protein Domain Structure
References
(Earliest) J:42300 Powell SM et al., "Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase." FEBS Lett 1992 May 25;303(1):4-10
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), "The Transcriptional Landscape of the Mammalian Genome" Science 2005;309(5740):1559-1563
All references(10)
Other
accession IDs 		MGD-MRK-1165, MGI:2138197
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
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