Symbol
Name
ID
|
|
|
Synonyms
|
Adh-3, Adh-3e, Adh-3t, Adh3, Adh3-e, Adh3-t, Adh4, Adt-1, IV ADH
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(28)
|
Alleles
and
phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Homozygous mutation of this gene results in defective ethanol clearance and reduced metabolism of retinal to retinoic acid.
|
|
|
Polymorphisms
|
SNPs within 2kb(128 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (12 records)
Data Summary:
Assays (2)
Results (52)
Tissues (44)
Images (14)
Theiler Stages: 1,3,4,9,10,11,12,13,14,15,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
9 |
| |
RNA in situ |
1 |
|
43 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(21)
Genomic(2)
cDNA(17)
Primer pair(2)
Microarray probesets(3)
|
|
Pathways
|
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR002085 |
Alcohol dehydrogenase superfamily, zinc-containing |
| IPR002328 |
Alcohol dehydrogenase, zinc-containing, conserved site |
| IPR011032 |
GroES-like |
| IPR013149 |
Alcohol dehydrogenase, zinc-binding |
| IPR013154 |
Alcohol dehydrogenase GroES-like |
| IPR016040 |
NAD(P)-binding domain |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:5932
Holmes RS,
"The genetics of alpha-hydroxyacid oxidase and alcohol dehydrogenase in the mouse: evidence for multiple gene loci and linkage between Hao-2 and Adh-3."
Genetics 1977 Dec;87(4):709-16
(Latest)
J:121381
Hu P et al.,
"Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal."
Biochim Biophys Acta 2007 Apr;1770(4):694-705
|
All references(55)
|
Other
accession IDs
|
MGD-MRK-1116, MGD-MRK-1117, MGD-MRK-1118, MGD-MRK-1125, MGD-MRK-1126, MGD-MRK-1127, MGD-MRK-1166, MGD-MRK-35651, MGI:107190, MGI:2139678, MGI:87927, MGI:87928
|
Analysis Tools
MGI BioMart
