References
Query Results -- Details
MGI Accession ID: MGI:60923
J Number: J:12687
Other Accession IDs:
Title: Gene trees and the origins of inbred strains of mice [see comments]
Authors: Atchley WR; Fitch WM
Journal: Science
Volume: 254
Issue: 5031
Date: 1991 Oct 25
Year: 1991
Pages: 554-8
Review Status: Peer Reviewed
Abstract:
Extensive data on genetic divergence among 24 inbred strains of mice provide an opportunity to examine the concordance of gene trees and species trees, especially whether structured subsamples of loci give congruent estimates of phylogenetic relationships. Phylogenetic analyses of 144 separate loci reproduce almost exactly the known genealogical relationships among these 24 strains. Partitioning these loci into structured subsets representing loci coding for proteins, the immune system and endogenous viruses give incongruent phylogenetic results. The gene tree based on protein loci provides an accurate picture of the genealogical relationships among strains; however, gene trees based upon immune and viral data show significant deviations from known genealogical affinities.
