Symbol
Name
ID
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Genetic Map
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Chromosome 2
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Syntenic
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Mapping data(
1)
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(26)
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Alleles
and
phenotypes
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All alleles(5) :
Targeted, knock-out(1)
Gene trapped(4)
| Mice homozygous for a null allele do not exhibit any abnormal phenotype. |
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Polymorphisms
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SNPs within 2kb(235 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (2 records)
Data Summary:
Assays (1)
Results (8)
Tissues (4)
Theiler Stages: 28
| |
Assay Type |
Assays |
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Results |
| |
Northern blot |
1 |
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8 |
cDNA source data(18)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(20)
Genomic(1)
cDNA(19)
Microarray probesets(1)
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Other database
links
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Protein
domains
|
| InterPro ID |
Description |
| IPR000095 |
PAK-box/P21-Rho-binding |
| IPR000719 |
Protein kinase, catalytic domain |
| IPR002290 |
Serine/threonine-protein kinase domain |
| IPR011009 |
Protein kinase-like domain |
| IPR015750 |
Serine/threonine-protein kinase, Pak-related |
| IPR017441 |
Protein kinase, ATP binding site |
| IPR017442 |
Serine/threonine-protein kinase-like domain |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:85954
Qu J et al.,
"PAK4 kinase is essential for embryonic viability and for proper neuronal development."
Mol Cell Biol 2003 Oct;23(20):7122-33
(Latest)
J:141962
Nekrasova T et al.,
"Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion."
Dev Biol 2008 Oct 1;322(1):95-108
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All references(5)
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Analysis Tools
MGI BioMart