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Dnd1 Gene Detail
 Symbol
Name
ID
Dnd1
dead end homolog 1 (zebrafish)
MGI:2447763


Nomenclature History
Synonyms MGC:41452, RBMS4, Ter
Genetic Map
Chromosome 18
20.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr18:36923325-36925868 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Dnd1 ± 2 cM)
TreeFam: TF314932
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000034043 VEGA Gene Model | MGI Sequence Detail 2544 C57BL/6J ± Kb
transcript NM_173383 RefSeq | MGI Sequence Detail 1490 C57BL/6
polypeptide Q6VY05 UniProt | EBI | MGI Sequence Detail 352 Not Applicable
For the selected sequences
All sequences(14)
Alleles
and
phenotypes
All alleles(2) : Gene trapped(1) Spontaneous(1)
A semidominant mutation in the 129/Sv strain markedly increases the frequency of testicular teratomas. Homozygous males are germ cell deficient and sterile, while homozygous females have small ovaries, but usually breed.
Polymorphisms SNPs within 2kb(34 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(7)
Process germ cell development, multicellular organismal development...
Component cytoplasm, nucleus...
Function nucleic acid binding, nucleotide binding...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (20)    Results (98)    Tissues (48)    Images (26)
Theiler Stages: 11,13,15,19,20,21,22,23,28
  Assay Type Assays   Results
      Western blot 13   46
      RT-PCR 3   5
      RNA in situ 2   38
      Northern blot 2   9
cDNA source data(4)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(7) cDNA(5) Primer pair(2) Antibodies(3)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000044595
DoTS DT.110785857, DT.91336407, DT.94153682
UniGene 234464
DFCI TC1587573
NIA Mouse Gene Index U053686
Entrez Gene 213236
VEGA Gene Model OTTMUSG00000034043
International Mouse Knockout Project Status Dnd1
Protein
domains
InterPro ID Description
IPR000504 RNA recognition motif, RNP-1
IPR012677 Nucleotide-binding, alpha-beta plait
Graphical View of Protein Domain Structure
References
(Earliest) J:29502 Stevens LC, "A new inbred subline of mice (129-terSv) with a high incidence of spontaneous congenital testicular teratomas." J Natl Cancer Inst 1973 Jan;50(1):235-42
(Latest) J:149469 Cook MS et al., "BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice." Dev Biol 2009 Apr 15;328(2):377-83
All references(23)
Other
accession IDs
MGD-MRK-15041, MGI:98710

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
Web browser compatibility
The Jackson Laboratory