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Npsr1 Gene Detail
 Symbol
Name
ID
Npsr1
neuropeptide S receptor 1
MGI:2441738

Nomenclature History
Synonyms 9330128H10Rik, Gpr154, PGR14, VRR1
Genetic Map
Chromosome 9
Syntenic
 
Mapping data( 1)
Sequence Map
Chr9:23902440-24120842 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: neuropeptide S receptor
TreeFam: TF106499
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000024228 VEGA Gene Model | MGI Sequence Detail 218403 C57BL/6J ± Kb
transcript NM_175678 RefSeq | MGI Sequence Detail 3791 C57BL/6
polypeptide Q8BZP8 UniProt | EBI | MGI Sequence Detail 371 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Gene trapped(1)
Mice homozygous for a knock-out allele exhibit decreased airway resistance when treated with high concentrations of U-46619.
Polymorphisms SNPs within 2kb(788 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway...
Component integral to membrane, membrane...
Function G-protein coupled receptor activity, receptor activity...
External Resources: FuncBase
Expression cDNA source data(5)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(7) cDNA(5) Other(2)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000043659
DoTS DT.101712788, DT.94128957
Consensus CDS Project CCDS22930.1
UniGene 130824
DFCI TC1589877, TC1621626
NIA Mouse Gene Index U010172
Entrez Gene 319239
VEGA Gene Model OTTMUSG00000024228
International Mouse Knockout Project Status Npsr1
Protein
domains
InterPro ID Description
IPR000276 7TM GPCR, rhodopsin-like
IPR001817 Vasopressin receptor
IPR017452 GPCR, rhodopsin-like superfamily
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs" Nature 2002;420():563-573
(Latest) J:153146 Duangdao DM et al., "Behavioral phenotyping of neuropeptide S receptor knockout mice." Behav Brain Res 2009 Dec 14;205(1):1-9
All references(4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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